The main difference between these two terminologies is that the Smooth Endoplasmic Reticulum is known for stocking the lipids and proteins. It is not bounded by ribosomes. Whereas, the Rough Endoplasmic Reticulum is bounded by the ribosomes and also stores proteins. Learn the difference between smooth endoplasmic reticulum and rough endoplasmic reticulum.
Character Smooth Endoplasmic Reticulum (SER) Rough Endoplasmic Reticulum (RER)
Definition Smooth Endoplasmic Reticulum does not have ribosomes on its membrane. Rough Endoplasmic Reticulum possesses ribosomes attached to its membrane.
Organized It is organized of vesicles and tubules. It is organized of cisternae and a few tubules.
Found It is present near the cell membrane. It is present near the cytoplasm.
Formation SER gives rise to Spherosomes/ Oleosomes. RER helps in the formation of lysosomes.
Composed of It is composed of the tubules. It is composed of the cisternae.
Synthesis Synthesises glycogen, lipids, and steroids. It participates in the synthesis of enzymes and proteins.
Connection SER may be connected to plasmalemma and is peripheral. RER is connected with the nuclear envelope and is internal.
Development Develops from Rough Endoplasmic Reticulum. It might develop from the nuclear envelope.
Ribophorins It lacks in Ribophorins. It consists of ribophorins and helps ribosomes attach to ER
Provide Provides vesicles for cis-face of the Golgi apparatus. Provides proteins and lipids for the Golgi apparatus.
Produces It produces lipids and proteins. It produces proteins.